Harnessing the In-Vitro-In-Vivo Correlation in Drug Development

There are instances in drug development where modifications are made to a drug’s composition, formulation, equipment used, or manufacturing processes.  These modifications require reassessment of the modified product to ensure the same pharmacological behavior. When a strong in-vitro-in-vivo correlation (IVIVC) is made, it effectively serves as a surrogate to costly in vivo bioequivalence studies, for […]